Local controlled release of simvastatin and PDGF from core/shell microspheres promotes bone regeneration in vivo
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چکیده
منابع مشابه
Local controlled release of simvastatin and PDGF from core/shell microspheres promotes bone regeneration in vivo
Simvastatin is demonstrated to be a potent stimulator for bone formation. However, a high dosage of simvastatin is required to induce bone regeneration in systematic administration, which may result in various side effects. Here we achieved the local administration of simvastatin through fabricating core/shell microspheres. Meanwhile, the addition of platelet derived growth factor (PDGF) encaps...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra01503h